


Precision Medicine: An Introduction to Umbrella and Basket Trials
Example of a real umbrella trial. Study scheme of the lung cancer master protocol (Lung-MAP–NCT03851445) trial. From Ouma L.O. et al. (2022) Front. Med. 9:1037439. doi: 10.3389/fmed.2022.1037439 In recent decades, cancer treatment has evolved from relying on...
Call for Public Review: Updated Guidance on Inclusive Language in Medical and Scientific Publications
In the realm of medical and scientific publishing, the precision and respect embedded in our language are crucial. The choice of terminology when describing individuals and groups can profoundly influence the clarity and fairness of our communications. Inclusive...
Barriers to cancer clinical trials participation
Ongoing cancer clinical trials in Africa in 2020 From Unger J.M. et al. JNCI J Natl Cancer Inst 2019. * Circles represent individual clinical trials * Colors of the circles represent the study’s primary sponsor type The cancer clinical trials context Clinical...
Strategies for the future of clinical research: decentralised clinical trials
Challenges with traditional clinical trials The traditional clinical trials system acts as a quality funnel for the development and implementation of new drugs, devices and health system interventions. They are centred around the trial site(s). The trial protocols...